an·guish [anguish anguishes anguished anguishing] BrE [ˈæŋɡwɪʃ]
NAmE [ˈæŋɡwɪʃ]
noun uncountable (formal)
severe pain, mental suffering or unhappiness
He groaned in anguish.
Tears of anguish filled her eyes.
Derived Word: anguished
Word Origin:
Middle English: via Old French from Latin angustia ‘tightness’, (plural) ‘distress’, from angustus ‘narrow’.
Example Bank:
He looked across at Kate's anguished face.
Jack looked anguished, almost desperate.
She read the letter, gave an anguished cry and collapsed.
Example Bank:
He suffered the anguish of watching his son go to prison.
His mouth felt dry with anguish.
In her anguish, she turned to her father for help.
The loss of a pet can cause some people real anguish.
his anguish at the death of his son
to cry out/groan/scream in anguish

Webster's 1913 Dictionary:
n.1.Extreme pain, either of body or mind; excruciating distress.
But they hearkened not unto Moses for anguish of spirit, and for cruel bondage.
Anguish as of her that bringeth forth her first child.
v. t.1.To distress with extreme pain or grief.

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