des·pite AW BrE [dɪˈspaɪt]
NAmE [dɪˈspaɪt]
1. used to show that sth happened or is true although sth else might have happened to prevent it
Syn: in spite of
Her voice was shaking despite all her efforts to control it.
Despite applying for hundreds of jobs, he is still out of work.
She was good at physics despite the fact that she found it boring.
2. despite yourself used to show that sb did not intend to do the thing mentioned
Syn: in spite of
He had to laugh despite himself.
Word Origin:
[despite] Middle English (originally used as a noun meaning ‘contempt, scorn’ in the phrase in despite of): from Old French despit, from Latin despectus ‘looking down on’, past participle (used as a noun) of despicere, from de- ‘down’ + specere ‘look at’.
Language Bank:
Ways of saying ‘but’
Politicians have promised to improve road safety. So far, however , little has been achieved.
Despite clear evidence from road safety studies, no new measures have been introduced.
Politicians have promised to improve road safety. In spite of this / Despite this , little has been achieved so far.
Although politicians have promised to improve road safety, little has been achieved so far.
Some politicians claim that the new transport policy has been a success. In fact , it has been a total disaster.
Government campaigns have had a measure of success, but the fact remains that large numbers of accidents are still caused by careless drivers.
Language Bank at nevertheless

WordNet Dictionary:
1. lack of respect accompanied by a feeling of intense dislike
- he was held in contempt
- the despite in which outsiders were held is legendary
Syn: contempt, disdain, scorn
2. contemptuous disregard
- she wanted neither favor nor despite

Webster's 1913 Dictionary:
n.1.Malice; malignity; spite; malicious anger; contemptuous hate.
With all thy despite against the land of Israel.
2.An act of malice, hatred, or defiance; contemptuous defiance; a deed of contempt.
A despite done against the Most High.
In despite
in defiance of another's power or inclination.
In despite of
in defiance of; in spite of. See under Spite.
In your despite
in defiance or contempt of you; in spite of you.
v. t.1.To vex; to annoy; to offend contemptuously.
[imp. & p. p. Despited; p. pr. & vb. n. Despiting.]
prep.1.In spite of; against, or in defiance of; notwithstanding; as, despite his prejudices.

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